70+ Clinical Studies
3 Billion CFU Per Lozenge
4 Clinically Studied Strains
Made in the Netherlands
Made for Daily Use

WHY ORALBIOME PRO

Daily support for the oral microbiome

Gum comfort

L. reuteri is included for daily oral microbiome support and gum comfort.

Fresh breath support

BLIS K12 helps support fresher breath by working where odour-causing bacteria can build up.

Plaque balance

BLIS M18 is selected to support a balanced oral environment after brushing and flossing.

One daily habit

A slow-dissolving lozenge fits into the evening routine without rinsing or refrigeration.

YOUR DAILY RITUAL

4 steps. 60 seconds. Done.

Step 01
Step 01: Brush & Floss

Brush & Floss

Complete your regular oral hygiene routine as normal.

Step 02
Step 02: Dissolve One Lozenge

Dissolve One Lozenge

Place one OralBiome Pro lozenge on your tongue. Let it dissolve slowly, do not chew.

Step 03
Step 03: Let It Dissolve or Brush

Let It Dissolve or Brush

Let the lozenge dissolve on your teeth, or gently brush it across your teeth with a toothbrush.

Step 04
Step 04: Let Probiotics Colonise

Let Probiotics Colonise

Avoid eating or drinking for 30 minutes. The beneficial bacteria need time to settle in.

For best results, use daily before bed. Each jar contains a 30-day supply.

PREMIUM INGREDIENTS

It’s what’s on the inside that counts.

Swipe

VISIBLE BALANCE

A brighter-looking smile starts with balance.

OralBiome Pro is not a bleaching shortcut. It supports the oral microbiome after brushing, so your mouth feels cleaner and your natural smile looks fresher over time.
  • Supports natural teeth whitening by helping keep the mouth environment balanced
  • 3 billion CFU from 4 clinically studied oral strains
  • Designed as the final step after brushing and flossing
BeforeClean teeth, unstable balance

Before

Clean teeth, unstable balance

Brushing helps remove buildup, but the mouth can still feel coated when the oral microbiome is out of balance.

After 30 daysFresher, brighter-looking finish

After 30 days

Fresher, brighter-looking finish

Daily probiotic support helps maintain a cleaner mouth environment, supporting fresh breath, gum comfort and a naturally polished look.

COMPARISON

Not all oral care is created equal.

Unlike traditional mouthwash and broad antibacterial care, OralBiome Pro is designed to support oral microbiome balance after cleaning.

Feature

Mouthwash

0

/ 7

Antibacterial Toothpaste

0

/ 7

OralBiome Pro

0

/ 7
Cleans unwanted bacteria
Supports beneficial bacteria
Addresses bad breath at the source
Supports gum health long-term
Partially
Supports oral microbiome balance
Made for daily use
Clinically studied ingredients
Varies
70+ studies

The clear winner

OralBiome Pro outperforms in 7/7 categories — the only oral care solution that restores your microbiome.

COMPARISON

Not all oral care is created equal.

Unlike traditional mouthwash and broad antibacterial care, OralBiome Pro is designed to support oral microbiome balance after cleaning.

0 Mouthwash
0 Toothpaste
0 OralBiome
Swipe to compare

1 / 7

Cleans unwanted bacteria

Mouthwash
Toothpaste
OralBiome

2 / 7

Supports beneficial bacteria

Mouthwash
Toothpaste
OralBiome

3 / 7

Addresses bad breath at the source

Mouthwash
Toothpaste
OralBiome

4 / 7

Supports gum health long-term

Mouthwash
Toothpaste Partially
OralBiome

5 / 7

Supports oral microbiome balance

Mouthwash
Toothpaste
OralBiome

6 / 7

Made for daily use

Mouthwash
Toothpaste
OralBiome

7 / 7

Clinically studied ingredients

Mouthwash
Toothpaste Varies
OralBiome 70+ studies

OralBiome Pro wins 7/7 categories. The only product that restores instead of destroys.

IMPORTANT INFORMATION

Safety & Usage

IMPORTANT INFORMATION

OralBiome Pro is designed for daily oral care use as a dissolvable lozenge.

  • Food supplement. Recommended use: dissolve 1 lozenge daily after brushing and flossing.
  • Do not exceed the recommended daily dose. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle.
  • Keep out of reach of young children.
  • Contains xylitol. Excessive consumption may produce laxative effects.
  • Keep away from pets, especially dogs.
  • Do not give to children who cannot safely dissolve a lozenge. Choking risk applies to young children.
  • If you are pregnant, breastfeeding, taking medication, or have a medical condition, consult a healthcare professional before use.
  • Store in a cool, dry place below 25°C. Keep the container tightly closed.
  • For best results, use as part of a complete daily oral care routine including brushing and flossing.

REAL RESULTS

What our customers are saying

5.0
Based on 144 verified reviews
HAVE QUESTIONS?

Frequently Asked Questions

Everything you need to know about OralBiome Pro. Can't find your answer? Contact us at info@calqix.com

After brushing and flossing, place one lozenge on your tongue and let it dissolve slowly. Do not chew. Avoid eating or drinking for 30 minutes afterwards to allow the probiotic strains to colonise your oral cavity. For optimal results, use daily before bed — this gives the beneficial bacteria the longest uninterrupted window to establish themselves.

Most users report fresher breath within the first 5–7 days. For noticeable improvements in oral comfort, consistent daily use for 4 to 8 weeks is typically needed. Your oral microbiome took years to become imbalanced; restoring it is a gradual process, not an overnight fix. Clinical studies on L. reuteri observed meaningful changes in gum-related markers at the 4-week mark.

Gut probiotics are encapsulated to survive stomach acid and colonise your intestines. OralBiome Pro is designed to dissolve in your mouth, delivering clinically studied bacterial strains directly to the oral cavity, where they're needed. The strains in our formula (L. reuteri, S. salivarius K12, S. salivarius M18) have been specifically researched for oral health benefits, not digestive ones.

OralBiome Pro is formulated for adults. Do not give to children who cannot safely dissolve a lozenge — choking risk applies to young children. For children over 12, consult a healthcare professional before use. The probiotic strains in our formula have been studied in paediatric populations with favourable safety profiles.

Yes, but timing matters. Use OralBiome Pro after mouthwash, never before. Antibacterial mouthwash can reduce the viability of the probiotic strains if used immediately after. We recommend waiting at least 30 minutes after mouthwash before dissolving your lozenge. Ideally, the best routine is: brush, floss, lozenge, sleep.

No. OralBiome Pro is shelf-stable at room temperature below 25 degrees Celsius. Store in a cool, dry place away from direct sunlight. The jar is designed to protect the probiotic strains from moisture. No special storage is needed. Keep it on your nightstand or in your bathroom cabinet.

The strains in OralBiome Pro, particularly L. reuteri, have been used in clinical studies involving pregnant women without reported adverse effects. However, as with any food supplement during pregnancy or breastfeeding, we recommend consulting your healthcare provider before starting use. Your doctor knows your individual circumstances best.

Your first jar ships immediately after ordering. Subsequent deliveries are automatic every 30 days, or 60 to 90 days if you prefer. You choose the frequency. You save 20% compared to one-time purchases. There are no commitments. You can skip a month, change your delivery frequency, or cancel entirely from your account dashboard with one click. No phone calls, no retention tricks, no penalties.

Yes, instantly, anytime. Log in to your account at calqix.com, go to your subscription, and click pause or cancel. Changes take effect immediately. If you pause, your subscription resumes automatically after the skipped period. If you cancel, you will not be charged again. We also offer a 60-day money-back guarantee on your first order if you are not satisfied.

The primary strain in OralBiome Pro, Lactobacillus reuteri, has been researched in over 70 peer-reviewed clinical studies for oral health applications. These studies have explored its role in supporting gum health, maintaining oral microbiome balance, and contributing to overall oral comfort. S. salivarius K12 has been studied for over 30 years for its role in supporting fresh breath by helping maintain a balanced oral bacterial environment. We maintain a research page at calqix.com/research with direct links to published studies.

Start your 30-day oral microbiome routine.

One Fresh Mint lozenge after brushing and flossing. Simple enough to stay consistent.

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